Natural Progesterone Questions & Answers

The most effective method of restoring natural progesterone levels is with the proper supplementation of transdermally applied natural progesterone. ProgesterAll is a fragrance-free cream that contains 20 milligrams (mg) of USP Natural Progesterone per 1/4 teaspoon of cream. Its unique liposome-mediated delivery system ensures rapid absorption of the ingredients into the skin so that they can be stored in the underlying fatty tissues for transmission to the bloodstream.

Should I use natural progesterone?

YES, if you experience any of these symptoms:

  • Acceleration of the aging process
  • Allergies (asthma, hives, rashes)
  • Autoimmune disorders such as lupus
  • Breast tenderness (cysts, lumps)
  • Cervical dysplasia
  • Decreased sex drive
  • Depression with anxiety or agitation
  • Fat gain around abdomen, hips, thighs
  • Fatigue
  • Fibrocystic breasts
  • Gallbladder disease
  • Hair loss
  • Headaches
  • Hot flashes
  • Hypertension
  • Hypoglycemia
  • Inability to focus or memory loss
  • Increased blood clotting (risk of strokes)
  • Infertility or miscarriage
  • Irregular menstrual periods
  • Irritability or mood swings
  • Insomnia
  • Osteoporosis
  • PMS
  • Premenopausal bone loss
  • Prostate inflammation
  • Sluggish metabolism
  • Uterine cancer or uterine fibroids
  • Water retention and bloating

I am already taking hormones from my doctor, why should I switch to natural progesterone?

Dr. Lee mentions in his books that natural hormones are simply an alternative to hormone replacement therapy (HRT). Synthetic progesterone (known as progestins) has many side effects and synthetic estrogen may be dangerous to your health—especially if taken without natural progesterone. If someone is taking estrogen (HRT), a gradual step is to start natural progesterone cream and gradually reduce the estrogen dose. Reduce estrogen by one-half every month for three months, then discontinue use of estrogen.

Please note: If you are using birth control pills or injections, it is important that you discontinue use when you start on natural progesterone.

I’m postmenopausal. Will I start menstruating again if I use natural hormones?

Occasionally, upon beginning use of natural hormone supplementation, a postmenopausal woman could experience some breakthrough bleeding or a “period.” This is a perfectly normal response and is nothing to cause alarm. The progesterone is simply causing the body to rid itself of excess stored estrogen which can sometimes stimulate a uterine shedding—thus breakthrough bleeding. It may take three to six months to regulate your cycle.

I have facial hair—especially above my upper lip—that requires shaving occasionally. What causes this?

This is a condition called “hirsutism” (defined as excessive growth of facial and body hair). It indicates that there is a hormonal imbalance between estrogen, testosterone (the dominant male hormone), and progesterone. Progesterone acts as a regulator for the entire endocrine system. A woman who has the hirsute problem probably has PMS, too. Both menopausal and menstruating women have reported that facial hair (and body hair) decreased or completely disappeared after three to six months of regular application of cream as previously described. Natural progesterone is needed to affect proper hormonal balance.

Is natural progesterone useful after a hysterectomy and for menopausal women?

Many medical authorities tell female patients who are postmenopausal that osteoporosis is inevitable. John R. Lee, MD proved this often repeated statement is simply untrue. The results of his ongoing clinical study with women are noteworthy. Patients have experienced new bone density ranging from 5 to 40 percent for women who have used natural progesterone cream from 6 to 48 months. His results also indicated this therapy is successful even several decades after menopause. One of his elderly patients has been using natural progesterone cream for many years and has a greater than 50 percent new bone density as proven by dualphoton absorptiometry. Dr. Lee found osteoporosis may be prevented or reversible in many cases.

Where do I apply natural progesterone?

Natural progesterone in a moisturizing cream can be applied to the face, neck, chest, inner arms, palms of hands, and the soles of the feet. ProgesterAll cream can be applied to the same capillary beds for as long as needed. The cream is readily absorbed and leaves no trace after a few minutes. During absorption, the progesterone bypasses the liver and goes to specific receptor sites.

Please note: Everyone is different. Some women and men require more progesterone cream to help alleviate symptoms, while others can use less. For the first 3 months, use one 2 oz. tube per month. Next, try cutting back on the amount of natural progesterone each month until estrogen dominant symptoms occur. Then return to the last dosage used without symptoms.

When do I use natural progesterone cream?

According to Dr. John R. Lee, use 1/8 to 1/4 teaspoon (1/8 tsp = 2 pea-shaped dots as wide as the dot on the ProgesterAll tube, 1/4 tsp = 4 pea-shaped dots) two times per day for the following:

PMS: Start applying cream 12 days after the first day of your period and continue through day 26-28 (depending on length of cycle).

Premenopause: Start applying cream 8 days after the first day of your period and use through day 26-28.

Irregular Periods: Start applying cream 10 days after the first day of your period and stop on day 28. If your period begins before day 28, discontinue use. Start counting to day 10 and resume use and stop on day 28. It may take 3 to 6 months to regulate cycle.

Hysterectomies, Menopause, Postmenopause, or Osteoporosis: Apply for 25 consecutive days. Stop for five days, then resume use. Repeat monthly.

Men: Use 1/8 teaspoon two times per day, all of the time. No break needed.

What exactly is natural progesterone and how does it differ from synthetic progesterone?

Natural progesterone is derived from diosgenin obtained from an organic tuber. Through a laboratory process, diosgenin is synthesized into the progesterone molecule identical to progesterone in the body. Pharmaceutical manufacturers alter the chemical makeup of progesterone in order to create synthetic progestins. Progestins in their altered molecular structure are not natural to the body and may cause many side effects.

Can natural progesterone help with fibrocystic breasts?

Fibrocystic breasts are merely a sign of estrogen dominance (relatively high estrogen levels and low progeterone levels). Therefore, using physiological doses of progesterone may eliminate fibrocystic breasts in a few months.

Can I use natural progesterone if there is family history of breast or uterine cancer?

Dr. Lee recommends it in his books on menopause, pre-menopause, and breast cancer. Breast cancer and endometrial cancer are two cancers that are related to gonadal (estrogens, progesterone, and testosterone) hormones. The cancers occur in tissues sensitive to these gonadal hormones. Unopposed estrogen is the only known cause of endometrial cancer, though there may be other factors involved. Unopposed estrogens are all thought to contribute to breast cancer.

Do natural hormones help vaginal dryness?

Vaginal dryness can occur in women of all ages for various reasons, but it is primarily present in postmenopausal women. Natural hormones in a cream base can be used intravaginally and has been very successful in treating vaginal dryness and vulvar atrophy associated with aging.

Are there any other benefits of natural progesterone use?

Additional benefits for women may include: improved brain function, diminished muscular aches and pains, improvement of skin problems including acne, seborrhea, rosacea, psoriasis and keratosis, and improved sleep pattern.

Have more questions?

Request a free 20-min consult with Sue Macco!

Appointments are available over the phone or in person at our office in Green Bay, WI.

About the experts:

The late John R. Lee, MD—author of the books What Your Doctor May Not Tell You About Menopause: The Breakthrough Book on Natural Progesterone, What Your Doctor May Not Tell You About Premenopause: Balance Your Hormones and Your Life From Thirty to Fifty, and What Your Doctor May Not Tell You About Breast Cancer: How Hormone Balance Can Save Your Life—successfully treated female patients with natural progesterone cream for over 15 years. Dr. Lee defined the signs of progesterone deficiency for women over 30 years of age to include swollen breasts, depression, low thyroid, fibrocystic breasts, water retention, weight gain, and loss of libido.

Jerilyn C. Pryor, MD—an endocrinology professor at the University of British Columbia—found through testing that 50% of the women in North America are severely deficient in progesterone by age 35. During the menopausal years, progesterone levels decrease to almost zero while estrogen levels only decrease by 40-60%. Dr. Lee defines the syndrome as “estrogen dominance.” When this hormonal imbalance occurs, the estrogen becomes toxic to the body. Treatment with natural progesterone restores the balance between these two main female hormones.

Jesse Hanley, MD has 15 years of medical practice in helping women bring balance back into their lives. She does this by balancing the emotional and spiritual aspects of their lives, as well as implementing the use of nutritional supplements and herbs and natural progesterone. Dr. Hanley focuses on empowering the patient with education and support systems that allow for personalized health care programs. Dr. Hanley has also coauthored the book, What Your Doctor May Not Tell You About Premenopause: Balancing Your Hormones and Your Life From Thirty to Fifty.

This product is not intended to diagnose, treat, cure, or prevent any disease or disorder. The statements contained herein have not been evaluated by the Food and Drug Administration.